Studies Pertaining to the Clinical Aspects of Malaria :: Health, Diseases

STUDIES PERTAINING TO THE clinical ASPECTS OF MALARIAMalaria is a complex condition exhibiting different manifestations in different split of the world depending on a few variables (Bin Mohanna et al. 2007). It was nominate that anemia and splenomegaly argon significantly associated with malaria among asymptomatic schoolchildren in Hajr valley, Hadramout (Bin Mohanna et al. 2007). Agina and Abd-Allah (1999) conducted a case control hire for the association of nitrous oxide levels to the bad and outcomes of cerebral malaria in Yemeni in-patients. The main(prenominal) clinical presentations in cerebral malaria patients were fever (76.4%), pallor (72.0%), hypoglycemia (67.4%), splenomegaly (60.5%), mysterious fainting (39.5%), tartness (18.6%), pulmonary oedema (13.9%), subconjunctival hemorrhage (13.9%), severe anemia (53.5%), and hemoglobinuria (6.9%) while in non-cerebral malaria patients the clinical presentations were fever (83.8%), pallor (67.7%), splenomegaly (66.0%), ja undice (9.7%), severe anemia (51.6%) and hypoglycemia (3.2%) . The serum level of nitric oxide was found to be higher in patients with cerebral malaria than those without. In cerebral malaria, nitric oxide levels were highly elevated in patients with deeper coma and longer duration of coma as head as those who died of cerebral malaria indicating its association with indices of distemper severity and outcome in patients with cerebral malaria (Agina and Abd-Allah, 1999).Sheiban et al. (1998) studied severe acute nephritic failure secondary to falciparum malaria among children receiving antimalarial therapy and other supportive therapy as well as peritoneal dialysis referred to the renal unit at Al-Thawra Hospital in Sanaa. In this study, it was concluded that significant differences were found between children who died (43.8%) compared to those who survived regarding age, plasma creatinine, plasma bilirubin, systolic and diastolic blood pressure, hemoglobin concentration, urine ou tput, and time from diagnosis to referral. However, gender, alanine aminotransferase level, degree of fever, plasma sodium or potassium levels were not found to be statistically different between these two groups (Sheiban et al. 1998). The occasion found that previous immunity, as indicated by presence of splenomegaly, was associated with better vista both in terms of lower mortality and less hemodynamic stochasticity which was evident in the older children owing to previous exposure to malarial infection, and therefore development of immunity (Sheiban et al. 1998). It is important to note that malaria was reported to be the cause of 5.9% of chronic renal failure in patients undergoing regular haemodialysis in Hadramout governorate (Badheeb 1998). Recently, Al Rohani et al. (2011) reported that malaria is the most common infectious disease causing acute renal failure (ARF) in Yemeni patients.